{
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  "Package": "MedxR",
  "Type": "Package",
  "Title": "Access Drug Regulatory Data via FDA and Health Canada APIs",
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  "Maintainer": "Renzo Caceres Rossi <arenzocaceresrossi@gmail.com>",
  "Description": "Provides functions to access drug regulatory data from\npublic RESTful APIs including the 'FDA Open API' and the\n'Health Canada Drug Product Database API', retrieving real-time\nor historical information on drug approvals, adverse events,\nrecalls, and product details. Additionally, the package\nincludes a curated collection of open datasets focused on\ndrugs, pharmaceuticals, treatments, and clinical studies. These\ndatasets cover diverse topics such as treatment dosages,\npharmacological studies, placebo effects, drug reactions,\nmisuses of pain relievers, and vaccine effectiveness. The\npackage supports reproducible research and teaching in\npharmacology, medicine, and healthcare by integrating reliable\ninternational APIs and structured datasets from public,\nacademic, and government sources. For more information on the\nAPIs, see: 'FDA API' <https://open.fda.gov/apis/> and 'Health\nCanada API'\n<https://health-products.canada.ca/api/documentation/dpd-documentation-en.html>.",
  "License": "GPL-3",
  "Language": "en",
  "URL": "https://github.com/lightbluetitan/medxr,\nhttps://lightbluetitan.github.io/medxr/",
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  "Repository": "https://lightbluetitan.r-universe.dev",
  "Date/Publication": "2026-01-14 09:00:09 UTC",
  "RemoteUrl": "https://github.com/lightbluetitan/medxr",
  "RemoteRef": "HEAD",
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  "NeedsCompilation": "no",
  "Packaged": {
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  "Author": "Renzo Caceres Rossi [aut, cre] (ORCID:\n<https://orcid.org/0009-0005-0744-854X>)",
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  "_published": "2026-05-22T08:40:37.205Z",
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      "date": "2025-10-16"
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      "date": "2026-01-14"
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  ],
  "_exports": [
    "aspirin_infarction_df",
    "ATC_code_tbl_df",
    "BCG_vaccine_df",
    "binding_df",
    "caffeine_matrix",
    "copd_drug_therapy_df",
    "dosage_tbl_df",
    "drug_prices_tbl_df",
    "drugsmisuse_tbl_df",
    "get_fda_adverse_events",
    "get_fda_drug_labels",
    "get_fda_drugs_approved",
    "get_fda_ndc_directory",
    "get_hc_active_ingredients",
    "get_hc_companies",
    "get_hc_din",
    "get_hc_drug_by_din",
    "get_hc_drug_products",
    "get_hc_forms",
    "get_hc_search_drug",
    "histamine_matrix",
    "naoh_digest_df",
    "oilvitaminA_df",
    "oral_anticoagulants_df",
    "parkinsons_list",
    "pharmacy_tbl_df",
    "placebos_df",
    "products_drug_tbl_df",
    "ratliver_df",
    "reactions_drug_tbl_df",
    "view_datasets_MedxR"
  ],
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    {
      "name": "aspirin_infarction_df",
      "title": "Aspirin after Myocardial Infarction",
      "object": "aspirin_infarction_df",
      "class": [
        "data.frame"
      ],
      "fields": [
        "study",
        "year",
        "d.asp",
        "n.asp",
        "d.plac",
        "n.plac"
      ],
      "rows": 7,
      "table": true,
      "tojson": true
    },
    {
      "name": "ATC_code_tbl_df",
      "title": "Drug Related ATC Codes",
      "object": "ATC_code_tbl_df",
      "class": [
        "spec_tbl_df",
        "tbl_df",
        "tbl",
        "data.frame"
      ],
      "fields": [
        "atc_code",
        "level_1",
        "code_1",
        "level_2",
        "code_2",
        "level_3",
        "code_3",
        "level_4",
        "code_4",
        "drugbank-id"
      ],
      "rows": 50,
      "table": true,
      "tojson": true
    },
    {
      "name": "BCG_vaccine_df",
      "title": "BCG Vaccine Effectiveness Studies",
      "object": "BCG_vaccine_df",
      "class": [
        "data.frame"
      ],
      "fields": [
        "trial",
        "author",
        "year",
        "tpos",
        "tneg",
        "cpos",
        "cneg",
        "ablat",
        "alloc"
      ],
      "rows": 13,
      "table": true,
      "tojson": true
    },
    {
      "name": "binding_df",
      "title": "Antibiotic Binding in Cows",
      "object": "binding_df",
      "class": [
        "data.frame"
      ],
      "fields": [
        "antibiotic",
        "binding"
      ],
      "rows": 12,
      "table": true,
      "tojson": true
    },
    {
      "name": "caffeine_matrix",
      "title": "The Effects of Caffeine",
      "object": "caffeine_matrix",
      "class": [
        "matrix",
        "array"
      ],
      "fields": [
        "Grade",
        "Without",
        "With"
      ],
      "rows": 28,
      "table": true,
      "tojson": true
    },
    {
      "name": "copd_drug_therapy_df",
      "title": "Pharmacologic Treatments for COPD",
      "object": "copd_drug_therapy_df",
      "class": [
        "data.frame"
      ],
      "fields": [
        "study",
        "year",
        "id",
        "treatment",
        "exac",
        "total"
      ],
      "rows": 94,
      "table": true,
      "tojson": true
    },
    {
      "name": "dosage_tbl_df",
      "title": "Treatment Dosages Defined by EUCAST",
      "object": "dosage_tbl_df",
      "class": [
        "tbl_df",
        "tbl",
        "data.frame"
      ],
      "fields": [
        "ab",
        "name",
        "type",
        "dose",
        "dose_times",
        "administration",
        "notes",
        "original_txt",
        "eucast_version"
      ],
      "rows": 759,
      "table": true,
      "tojson": true
    },
    {
      "name": "drug_prices_tbl_df",
      "title": "Unit Drug Prices",
      "object": "drug_prices_tbl_df",
      "class": [
        "spec_tbl_df",
        "tbl_df",
        "tbl",
        "data.frame"
      ],
      "fields": [
        "description",
        "currency",
        "cost",
        "unit",
        "parent_key"
      ],
      "rows": 208,
      "table": true,
      "tojson": true
    },
    {
      "name": "drugsmisuse_tbl_df",
      "title": "Pain Relievers Misuse in the US",
      "object": "drugsmisuse_tbl_df",
      "class": [
        "tbl_df",
        "tbl",
        "data.frame"
      ],
      "fields": [
        "caseid",
        "hydrocd",
        "oxycodp",
        "codeine",
        "tramadl",
        "morphin",
        "methdon",
        "vicolor"
      ],
      "rows": 100,
      "table": true,
      "tojson": true
    },
    {
      "name": "histamine_matrix",
      "title": "Histamine in Dogs",
      "object": "histamine_matrix",
      "class": [
        "matrix",
        "array"
      ],
      "fields": [
        "Before",
        "After1",
        "After3",
        "After5"
      ],
      "rows": 16,
      "table": true,
      "tojson": true
    },
    {
      "name": "naoh_digest_df",
      "title": "Digestibility of Straw Treated with NaOH",
      "object": "naoh_digest_df",
      "class": [
        "data.frame"
      ],
      "fields": [
        "horse",
        "ordinary",
        "naoh"
      ],
      "rows": 6,
      "table": true,
      "tojson": true
    },
    {
      "name": "oilvitaminA_df",
      "title": "Utilization of Vitamin A in Rats",
      "object": "oilvitaminA_df",
      "class": [
        "data.frame"
      ],
      "fields": [
        "type",
        "avit"
      ],
      "rows": 20,
      "table": true,
      "tojson": true
    },
    {
      "name": "oral_anticoagulants_df",
      "title": "Oral Anticoagulants in Coronary Artery Disease",
      "object": "oral_anticoagulants_df",
      "class": [
        "data.frame"
      ],
      "fields": [
        "study",
        "year",
        "intensity",
        "asp.t",
        "asp.c",
        "ai",
        "n1i",
        "ci",
        "n2i"
      ],
      "rows": 34,
      "table": true,
      "tojson": true
    },
    {
      "name": "parkinsons_list",
      "title": "Dopamine Agonists in Parkinson's Disease",
      "object": "parkinsons_list",
      "class": [
        "list"
      ],
      "fields": [],
      "table": false,
      "tojson": true
    },
    {
      "name": "pharmacy_tbl_df",
      "title": "Pharmacy Client Attendance",
      "object": "pharmacy_tbl_df",
      "class": [
        "tbl_df",
        "tbl",
        "data.frame"
      ],
      "fields": [
        "date",
        "hours",
        "weekday",
        "attendance"
      ],
      "rows": 17520,
      "table": true,
      "tojson": true
    },
    {
      "name": "placebos_df",
      "title": "Placebos and Pain Relief",
      "object": "placebos_df",
      "class": [
        "data.frame"
      ],
      "fields": [
        "Time",
        "Placebo",
        "Distr",
        "Asp",
        "Codis",
        "PlaceboRed"
      ],
      "rows": 7,
      "table": true,
      "tojson": true
    },
    {
      "name": "products_drug_tbl_df",
      "title": "Drug Product Records",
      "object": "products_drug_tbl_df",
      "class": [
        "tbl_df",
        "tbl",
        "data.frame"
      ],
      "fields": [
        "name",
        "labeller",
        "ndc-id",
        "ndc-product-code",
        "dpd-id",
        "ema-product-code",
        "ema-ma-number",
        "started-marketing-on",
        "ended-marketing-on",
        "dosage-form",
        "strength",
        "route",
        "fda-application-number",
        "generic",
        "over-the-counter",
        "approved",
        "country",
        "source",
        "parent_key"
      ],
      "rows": 3764,
      "table": true,
      "tojson": true
    },
    {
      "name": "ratliver_df",
      "title": "Drug Concentration in Rat Livers",
      "object": "ratliver_df",
      "class": [
        "data.frame"
      ],
      "fields": [
        "BodyWt",
        "LiverWt",
        "Dose",
        "DoseInLiver"
      ],
      "rows": 19,
      "table": true,
      "tojson": true
    },
    {
      "name": "reactions_drug_tbl_df",
      "title": "Drug Reactions",
      "object": "reactions_drug_tbl_df",
      "class": [
        "spec_tbl_df",
        "tbl_df",
        "tbl",
        "data.frame"
      ],
      "fields": [
        "sequence",
        "left_drugbank_id",
        "left_drugbank_name",
        "right_drugbank_id",
        "right_drugbank_name",
        "parent_key"
      ],
      "rows": 69,
      "table": true,
      "tojson": true
    }
  ],
  "_help": [
    {
      "page": "aspirin_infarction_df",
      "title": "Aspirin after Myocardial Infarction",
      "topics": [
        "aspirin_infarction_df"
      ]
    },
    {
      "page": "ATC_code_tbl_df",
      "title": "Drug Related ATC Codes",
      "topics": [
        "ATC_code_tbl_df"
      ]
    },
    {
      "page": "BCG_vaccine_df",
      "title": "BCG Vaccine Effectiveness Studies",
      "topics": [
        "BCG_vaccine_df"
      ]
    },
    {
      "page": "binding_df",
      "title": "Antibiotic Binding in Cows",
      "topics": [
        "binding_df"
      ]
    },
    {
      "page": "caffeine_matrix",
      "title": "The Effects of Caffeine",
      "topics": [
        "caffeine_matrix"
      ]
    },
    {
      "page": "copd_drug_therapy_df",
      "title": "Pharmacologic Treatments for COPD",
      "topics": [
        "copd_drug_therapy_df"
      ]
    },
    {
      "page": "dosage_tbl_df",
      "title": "Treatment Dosages Defined by EUCAST",
      "topics": [
        "dosage_tbl_df"
      ]
    },
    {
      "page": "drug_prices_tbl_df",
      "title": "Unit Drug Prices",
      "topics": [
        "drug_prices_tbl_df"
      ]
    },
    {
      "page": "drugsmisuse_tbl_df",
      "title": "Pain Relievers Misuse in the US",
      "topics": [
        "drugsmisuse_tbl_df"
      ]
    },
    {
      "page": "get_fda_adverse_events",
      "title": "Search Adverse Events by Drug Name in FDA Adverse Event Reporting System",
      "topics": [
        "get_fda_adverse_events"
      ]
    },
    {
      "page": "get_fda_drug_labels",
      "title": "Search Drug Labels by Drug Name in FDA Drug Labeling Database",
      "topics": [
        "get_fda_drug_labels"
      ]
    },
    {
      "page": "get_fda_drugs_approved",
      "title": "Search FDA-Approved Drugs by Drug Name",
      "topics": [
        "get_fda_drugs_approved"
      ]
    },
    {
      "page": "get_fda_ndc_directory",
      "title": "Search National Drug Code (NDC) Directory by Drug Name",
      "topics": [
        "get_fda_ndc_directory"
      ]
    },
    {
      "page": "get_hc_active_ingredients",
      "title": "Get Active Ingredients from Health Canada Drug Product Database",
      "topics": [
        "get_hc_active_ingredients"
      ]
    },
    {
      "page": "get_hc_companies",
      "title": "Get Companies from Health Canada Drug Product Database",
      "topics": [
        "get_hc_companies"
      ]
    },
    {
      "page": "get_hc_din",
      "title": "Get All DINs from Health Canada Drug Product Database",
      "topics": [
        "get_hc_din"
      ]
    },
    {
      "page": "get_hc_drug_by_din",
      "title": "Get a Drug Product by DIN from Health Canada Drug Product Database",
      "topics": [
        "get_hc_drug_by_din"
      ]
    },
    {
      "page": "get_hc_drug_products",
      "title": "Retrieve Drug Products from Health Canada Drug Product Database",
      "topics": [
        "get_hc_drug_products"
      ]
    },
    {
      "page": "get_hc_forms",
      "title": "Get Pharmaceutical Forms from Health Canada Drug Product Database",
      "topics": [
        "get_hc_forms"
      ]
    },
    {
      "page": "get_hc_search_drug",
      "title": "Search Drug Products by Brand Name in Health Canada Drug Product Database",
      "topics": [
        "get_hc_search_drug"
      ]
    },
    {
      "page": "histamine_matrix",
      "title": "Histamine in Dogs",
      "topics": [
        "histamine_matrix"
      ]
    },
    {
      "page": "naoh_digest_df",
      "title": "Digestibility of Straw Treated with NaOH",
      "topics": [
        "naoh_digest_df"
      ]
    },
    {
      "page": "oilvitaminA_df",
      "title": "Utilization of Vitamin A in Rats",
      "topics": [
        "oilvitaminA_df"
      ]
    },
    {
      "page": "oral_anticoagulants_df",
      "title": "Oral Anticoagulants in Coronary Artery Disease",
      "topics": [
        "oral_anticoagulants_df"
      ]
    },
    {
      "page": "parkinsons_list",
      "title": "Dopamine Agonists in Parkinson's Disease",
      "topics": [
        "parkinsons_list"
      ]
    },
    {
      "page": "pharmacy_tbl_df",
      "title": "Pharmacy Client Attendance",
      "topics": [
        "pharmacy_tbl_df"
      ]
    },
    {
      "page": "placebos_df",
      "title": "Placebos and Pain Relief",
      "topics": [
        "placebos_df"
      ]
    },
    {
      "page": "products_drug_tbl_df",
      "title": "Drug Product Records",
      "topics": [
        "products_drug_tbl_df"
      ]
    },
    {
      "page": "ratliver_df",
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